7 results for "Synthetic Cathepsin Inhibitors" in Products
Synthetic Cathepsin Inhibitors
Cathepsins are a group of lysosomal proteases that have a key role in cellular protein turnover. The term cathepsin includes serine proteases (cathepsins A and G), aspartic proteases (cathepsin D and E) as well as the cysteine proteases (cathepsins B, C, F, H, K, L, O, S, W and Z).
Most cathepsins are endopeptidases, with the exception of cathepsin C and Z. Cathepsins are synthesized as inactive proenzymes, glycosylated post-translationally, and directed towards the lysosomal compartment by ...
Cathepsin inhibitor; interferes with autolysosomal digestion
| Chemical Name: | (2S,3S)-3-[[[(1S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic acid ethyl ester |
| Purity: | ≥98% |
Selective cathepsin B inhibitor
| Chemical Name: | N-[[(2S,3S)-3-[(Propylamino)carbonyl]-2-oxiranyl]carbonyl]-L-isoleucyl-L-proline |
| Purity: | ≥98% |
Potent and irreversible cysteine protease inhibitor
| Chemical Name: | (2S,3S)-3-[[[(1S)-1-[[[4-(Aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-2-oxiranecarboxylic acid |
| Purity: | ≥98% |
Potent cathepsin K inhibitor
| Chemical Name: | N-[1-[[(Cyanomethyl)amino]carbonyl]cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazolyl]benzamide |
| Purity: | ≥98% |
Cathepsin L inhibitor
| Chemical Name: | N-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophan-2-[[[2-[(2-ethylphenyl)amino]-2-oxoethyl]thio]carbonyl]hydrazide |
| Purity: | ≥97% |
Potent and selective cathepsin K inhibitor
| Chemical Name: | N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-(4-propylpiperazin-1-yl)benzamide |
| Purity: | ≥98% |
Potent cathepsin C inhibitor
| Chemical Name: | 4-Amino-N-[(1S)-1-cyano-2-(4'-cyano[1,1'-biphenyl]-4-yl)ethyl]tetrahydro-2H-pyran-4-carboxamide |
| Purity: | ≥98% |
