7 results for "Synthetic Cathepsin Inhibitors" in Products

Synthetic Cathepsin Inhibitors

Cathepsin A, also known as lyososomal carboxypeptidase A, is a member of the serine carboxypeptidase family. Cathepsin A is a multifunctional enzyme that expresses deaminidase and esterase activities at neutral pH and carboxypeptidase activity at acidic pH. Cathepsin A is synthesized as a single-chain precursor and processed into heavy (32 kDa) and light (20 kDa) chains, which are linked by disulfide bonds.

Selective cathepsin B inhibitor

Chemical Name: N-[[(2S,3S)-3-[(Propylamino)carbonyl]-2-oxiranyl]carbonyl]-L-isoleucyl-L-proline
Purity: ≥98%
Selective cathepsin B inhibitor
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Cathepsin inhibitor; interferes with autolysosomal digestion

Chemical Name: (2S,3S)-3-[[[(1S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic acid ethyl ester
Purity: ≥98%
Cathepsin inhibitor; interferes with autolysosomal digestion
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Potent and irreversible cysteine protease inhibitor

Chemical Name: (2S,3S)-3-[[[(1S)-1-[[[4-(Aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-2-oxiranecarboxylic acid
Purity: ≥98%
Potent and irreversible cysteine protease inhibitor
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Potent cathepsin K inhibitor

Chemical Name: N-[1-[[(Cyanomethyl)amino]carbonyl]cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazolyl]benzamide
Purity: ≥98%
Potent cathepsin K inhibitor
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Cathepsin L inhibitor

Chemical Name: N-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophan-2-[[[2-[(2-ethylphenyl)amino]-2-oxoethyl]thio]carbonyl]hydrazide
Purity: ≥97%
Cathepsin L inhibitor
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Potent and selective cathepsin K inhibitor

Chemical Name: N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-(4-propylpiperazin-1-yl)benzamide
Purity: ≥98%
Potent and selective cathepsin K inhibitor
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Potent cathepsin C inhibitor

Chemical Name: 4-Amino-N-[(1S)-1-cyano-2-(4'-cyano[1,1'-biphenyl]-4-yl)ethyl]tetrahydro-2H-pyran-4-carboxamide
Purity: ≥98%
Potent cathepsin C inhibitor
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