Mouse SIGNR1 is a type II transmembrane protein that is a homolog of human DCSIGN (R). It is a C-type lectin expressed by marginal zone macrophages and by medullary and subcapsular macrophages in lymph nodes. SIGN R1 binds and mediates the uptake of dextran via mannose and fucose binding sites.
SIGNR1/CD209b Antibody (258829) [Dylight 350]
Novus Biologicals | Catalog # FAB1836D
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot
Label
DyLight 350 (Excitation = 353 nm, Emission = 432 nm)
Antibody Source
Monoclonal Rat IgG2B Clone # 258829
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse SIGNR1/CD209b
Ser76-Gly325
Accession # Q8CJ91
Ser76-Gly325
Accession # Q8CJ91
Specificity
Detects mouse SIGNR1/CD209b in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse SIGNR4 is observed.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2B
Applications for SIGNR1/CD209b Antibody (258829) [Dylight 350]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: SIGNR1/CD209b
Long Name
SIGN-related 1
Alternate Names
CD209b
Gene Symbol
Cd209a
Additional SIGNR1/CD209b Products
Product Documents for SIGNR1/CD209b Antibody (258829) [Dylight 350]
Product Specific Notices for SIGNR1/CD209b Antibody (258829) [Dylight 350]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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