Sildenafil citrate

Discontinued Product

3784 has been discontinued.
View all Phosphodiesterase Inhibitors products.
Description: Potent PDE5 inhibitor; orally active

Chemical Name: 1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate

Product Details
Citations (1)
Reviews

Biological Activity

Orally active, potent inhibitor of phosphodiesterase 5 (PDE5) (IC50 = 4 nM). Enhances nitric oxide-dependent relaxation of human corpus cavernosum in vitro. Promotes mobilization of hematopoietic stem cells (HSCs) in combination with AMD 3100 (Cat. No. 3299). Reduces pulmonary pressure and edema.

Technical Data

Formula:
C22H30N6O4S.C6H8O7
Solubility:
Soluble to 100 mM in DMSO
Storage:
Store the unopened product at room temperature. Do not use past expiration date.
CAS No:
171599-83-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

Product Datasheets

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Citation for Sildenafil citrate

The citations listed below are publications that use Tocris products. Selected citations for Sildenafil citrate include:

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