PCSK9 (Proprotein Convertase 9, is a serine endoprotease that is highly expressed in the liver, intestine, and kidney. PCSK9 promotes the degradation of low density lipoprotein receptor (LDLR) by inducing receptor degradation in the lysosome following its internalization. PCSK9 regulates the amounts of LDLR in the circulation and hence, modulates cholesterol levels. Nonsense or loss-of-function mutations in PCSK9 are associated with decreased plasma LDL cholesterol levels.
Simple Plex Control for Human Proprotein Convertase 9/PCSK9
R&D Systems | Catalog # 898101
Control for use with Human Proprotein Convertase 9/PCSK9 Simple Plex Cartridge Kit
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Key Product Details
Species
Human
Applications
Control, Simple Plex Automated Immunoassay
Product Summary for Simple Plex Control for Human Proprotein Convertase 9/PCSK9
INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human Proprotein Convertase 9/PCSK9 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.
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Formulation, Preparation, and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: Proprotein Convertase 9/PCSK9
Alternate Names
FH3, FHCL3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9, PCSK9
Gene Symbol
PCSK9
Additional Proprotein Convertase 9/PCSK9 Products
- All Products for Proprotein Convertase 9/PCSK9
- Proprotein Convertase 9/PCSK9 cDNA Clones
- Proprotein Convertase 9/PCSK9 ELISA Kits
- Proprotein Convertase 9/PCSK9 Lysates
- Proprotein Convertase 9/PCSK9 Primary Antibodies
- Proprotein Convertase 9/PCSK9 Proteins and Enzymes
- Proprotein Convertase 9/PCSK9 Simple Plex
Product Documents for Simple Plex Control for Human Proprotein Convertase 9/PCSK9
Certificate of Analysis
To download a Certificate of Analysis, please enter your Simple Plex catalog number and lot number in the search boxes below.
Product Specific Notices for Simple Plex Control for Human Proprotein Convertase 9/PCSK9
For research use only
Related Research Areas
Citations for Simple Plex Control for Human Proprotein Convertase 9/PCSK9
View all citations for the Simple Plex platform on Bio-Techne.com.
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