Relaxin-2, also called H2 relaxin, is a peptide hormone that plays an important role in female reproduction. It circulates in the blood as a disulfide-linked dimer of alpha and beta chains. Relaxin is best known as a hormone of parturition that promotes growth and softening of the cervix, development of the mammary gland, and has a marked impact on the uterus. In particular, it promotes angiogenesis, inhibits MMP production and activity, and downregulates estrogen receptor-alpha expression. Relaxin-2 confers its activity by binding to leucine-rich guanine nucleotide-binding (G-protein) coupled receptors, LGR7 and LGR8.
Simple Plex Discovery Control for Human Relaxin-2
R&D Systems | Catalog # 898218
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Product Summary for Simple Plex Discovery Control for Human Relaxin-2
Formulation, Preparation, and Storage
Shipping
Storage
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: Relaxin-2
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Product Documents for Simple Plex Discovery Control for Human Relaxin-2
Certificate of Analysis
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Product Specific Notices for Simple Plex Discovery Control for Human Relaxin-2
For research use only
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