Simple Plex Human TIMP-2 Cartridge
R&D Systems | Catalog # SPCKB-PS-006178
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Simple Plex cartridges are custom built to fit your needs. Choose from over 350 assays spanning human, mouse, rat, and non-human primate. Just select your sample type, cartridge size (16, 32, or 72 samples), and up to 8 analytes per cartridge. Customize this cartridge.
Key Product Details
Assay Length
Sample Type & Volume Required Per Well*
Sensitivity
Assay Range
Simple Plex Human TIMP-2 Cartridge Summary
*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay's minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.
Compatible Instruments
Ella Automated Immunoassay System
Product Specifications
Assay Type
Format
Species
Cross-reactivity
Interference
Precision
Intra-Assay Precision (Precision within an assay) Each control was tested multiple times in one TIMP-2 assay.
Inter-Assay Precision (Precision between assays) Replicates of each TIMP-2 control were tested in multiple assays performed by at least three technicians using two lots of reagents for human TIMP-2.
Cell Culture Supernates, EDTA Plasma, Heparin Plasma, Saliva, Serum, Urine
| Intra-Assay Precision | Inter-Assay Precision | |||
|---|---|---|---|---|
| Sample | 1 | 2 | 1 | 2 |
| n | 16 | 16 | 22 | 22 |
| Mean (pg/mL) | 183 | 9932 | 167 | 10,585 |
| Standard Deviation | 8.3 | 587 | 11.2 | 991 |
| CV% | 4.5 | 5.9 | 6.7 | 9.4 |
Recovery for Simple Plex Human TIMP-2 Cartridge
Recovery was not necessary as human TIMP-2 shows 5 points of natural linearity.
Linearity
Sample containing and/or spiked with high concentrations for human TIMP-2 were serially diluted with Sample Diluent to produce sample within the dynamic range of the assay.
Scientific Data Images for Simple Plex Human TIMP-2 Cartridge
Simple Plex Human TIMP-2 Assay Standard Curve
Data shown represents typical performance results for Lower Limit of Quantitation (LLOQ) and Upper Limit of Quantitation (ULOQ) for Simple Plex Human TIMP-2 Assay. Assay range is 20.5-12,500 pg/mL.Preparation and Storage
Shipping
Stability & Storage
Background: TIMP-2
TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.
Long Name
Alternate Names
Gene Symbol
Additional TIMP-2 Products
Product Documents for Simple Plex Human TIMP-2 Cartridge
Certificate of Analysis
To download a Certificate of Analysis, please enter your Simple Plex catalog number and lot number in the search boxes below.
Product Specific Notices for Simple Plex Human TIMP-2 Cartridge
For research use only
Related Research Areas
Citations for Simple Plex Human TIMP-2 Cartridge
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