382 results for "TIMP-2" in Products
TIMP-2 Products
TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.
| Reactivity: | Human |
| Sensitivity: | 0.064 ng/mL |
| Assay Range: | 0.156-10 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine) |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #89025 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | KO, IHC, WB, B/N, Dual ISH-IHC |
Simple Plex Human TIMP-2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer. Sample type indicated with PS (Plasma/Serum).
| Reactivity: | Human |
| Applications: | Simple Plex |
| Reactivity: | Human |
| Assay Range: | 31.2-2000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Source: | CHO |
| Accession #: | P16035 |
| Applications: | Inhibition Activity |
| Reactivity: | Mouse |
| Assay Range: | 7.81-500 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1A6 |
| Applications: | IHC, WB, Flow |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1A6 |
| Applications: | IHC, WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #127711 |
| Applications: | KO, ELISA(Cap) |
| Reactivity: | Human, Mouse, Rat, Bovine, Guinea Pig, +2 More |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #SPM356 |
| Applications: | IHC, WB, Flow, ICC/IF, CyTOF-ready |
| Reactivity: | Mouse |
| Source: | NS0 |
| Accession #: | NP_035724 |
| Applications: | Enzyme Activity |
| Reactivity: | Human |
| Source: | CHO |
| Applications: | WB |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Goat IgG Monoclonal Clone #40019A |
| Applications: | KO, IHC, WB |
| Reactivity: | Human, Mouse, Rat, Bovine, Guinea Pig, +2 More |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #3A4 |
| Applications: | IHC, WB, Flow, ICC/IF |
| Reactivity: | Human, Mouse, Rat, Bovine, Guinea Pig, +2 More |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #SPM356 |
| Applications: | IHC, WB, Flow, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #F27 P3 A4 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat, Bovine, Guinea Pig, +2 More |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #3A4 |
| Applications: | IHC, WB, Flow, ICC/IF, CyTOF-ready |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #3A4 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Porcine, Chicken, Rabbit, +1 More |
| Details: | Mouse IgG2A Monoclonal Clone #3A4 |
| Applications: | IHC, WB, ELISA |
Control for use with Human and Non-Human Primate TIMP-2 Simple Plex Assay Cartridge Kit
| Reactivity: | Human, Non-human Primate |
| Applications: | Ctrl, Simple Plex |
For use with catalog number DTM200
| Reactivity: | Human |
| Applications: | ELISA, Ctrl |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA(Det) |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat, Bovine, Guinea Pig, +2 More |
| Details: | Rabbit IgG Monoclonal Clone #TIMP2/2488R |
| Applications: | IHC |
Simple Plex Non-Human Primate TIMP-2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer. Sample type indicated by NP (Plasma/Serum).
| Reactivity: | Non-human Primate |
| Applications: | Simple Plex |