Simple Plex Mouse TIM-1/KIM-1/HAVCR Cartridge
R&D Systems | Catalog # SPCKB-MP-007124
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Key Product Details
Assay Length
Sample Type & Volume Required Per Well*
Sensitivity
Assay Range
Simple Plex Mouse TIM-1/KIM-1/HAVCR Cartridge Summary
*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay's minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.
Compatible Instruments
Ella Automated Immunoassay System
Product Specifications
Assay Type
Format
Species
Specificity
Cross-reactivity
Interference
Precision
Intra-Assay Precision (Precision within an assay) Each control was tested multiple times in one TIM-1/KIM-1/HAVCR assay.
Inter-Assay Precision (Precision between assays) Replicates of each TIM-1/KIM-1/HAVCR control were tested in multiple assays performed by at least three technicians using two lots of reagents for mouse TIM-1/KIM-1/HAVCR.
Cell Culture Supernates, EDTA Plasma, Heparin Plasma, Serum, Urine
| Intra-Assay Precision | Inter-Assay Precision | |||
|---|---|---|---|---|
| Sample | 1 | 2 | 1 | 2 |
| n | 16 | 16 | 39 | 39 |
| Mean (µL) | 26.5 | 1260 | 34.1 | 1629 |
| Standard Deviation | 1.39 | 44.5 | 2.97 | 121 |
| CV% | 5.3 | 3.5 | 8.7 | 7.4 |
Recovery for Simple Plex Mouse TIM-1/KIM-1/HAVCR Cartridge
Recovery for the mouse TIM-1/KIM-1/HAVCR assays was evaluated at three different spiked concentrations of TIM-1/KIM-1/HAVCR protein.
| Sample Type | Average % Recovery | Range % |
|---|---|---|
| EDTA Plasma (n=4) | 110 | 101-119 |
| Heparin Plasma (n=4) | 106 | 96-110 |
| Serum (n=4) | 109 | 102-116 |
Linearity
Samples containing and/or spiked with high concentrations of TIM-1/KIM-1/HAVCR were serially diluted with Sample Diluent to produce samples within the dynamic range of the assay.
Scientific Data Images for Simple Plex Mouse TIM-1/KIM-1/HAVCR Cartridge
Simple Plex Mouse TIM-1/KIM-1/HAVCR Assay Standard Curve
Data shown represents typical performance results for Lower Limit of Quantitation (LLOQ) and Upper Limit of Quantitation (ULOQ) for Simple Plex Mouse TIM-1/KIM-1/HAVCR Assay. Assay range is 2.91-4440 pg/mL.Preparation and Storage
Shipping
Stability & Storage
Background: TIM-1/KIM-1/HAVCR
TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.
Long Name
Alternate Names
Gene Symbol
Additional TIM-1/KIM-1/HAVCR Products
Product Documents for Simple Plex Mouse TIM-1/KIM-1/HAVCR Cartridge
Certificate of Analysis
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Product Specific Notices for Simple Plex Mouse TIM-1/KIM-1/HAVCR Cartridge
For research use only
Related Research Areas
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