Sipatrigine

Catalog # Availability Size / Price Qty
4044/10
4044/50
Sipatrigine | CAS No. 130800-90-7 | Voltage-gated Sodium Channel Blockers
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Description: NaV blocker; neuroprotective
Alternative Names: 619C89

Chemical Name: 2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine

Purity: ≥99%

Product Details
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Biological Activity

Blocker of voltage-dependent sodium channels (NaV). Inhibits glutamate release; displays neuroprotective activity in rat models of cerebral ischemia. Also thought to block Ca2+ channels. Analog of lamotrigine (Cat. No. 1611).

Technical Data

M.Wt:
372.68
Formula:
C15H16Cl3N5
Solubility:
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
130800-90-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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