SJF 0661

Tocris Bioscience | Catalog # 7464

Negative control for SJF 0628 (Cat. No. 7463)
Tocris Bioscience
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Key Product Details

Description

Negative control for SJF 0628 (Cat. No. 7463)

Product Description

SJF 0661 is the negative control for SJF 0628 (Cat. No. 7463). Binds BRAF without inducing degradation.

Product Specifications for SJF 0661

Molecular Weight

1010.19

Formula

C51H57F2N9O7S2

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

(2S,4S)-1-((S)-2-(2-(4-(4-(3-(2,6-Difluoro-3-(propylsulfonamido)benzoyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)piperazin-1-yl)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

CAS Number

2413035-43-3

PubChem ID

146502225

InChI Key

MBCAVOCJJAQHHT-NYNRYUPBSA-N

SMILES

CCCS(=O)(NC1=CC=C(C(C(C2=CNC3=NC=C(C4=CC=C(N5CCN(CC5)CC(N[C@@H](C(C)(C)C)C(N6C[C@H](C[C@H]6C(NCC7=CC=C(C8=C(N=CS8)C)C=C7)=O)O)=O)=O)C=C4)C=C23)=O)=C1F)F)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 101.02 100

Preparing Stock Solutions for SJF 0661

The following data is based on the product molecular weight 1010.19.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.99 mL 4.95 mL 9.90 mL
5 mM 0.20 mL 0.99 mL 1.98 mL
10 mM 0.10 mL 0.49 mL 0.99 mL
50 mM 0.02 mL 0.10 mL 0.20 mL

Calculators

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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Background References

References are publications that support the biological activity of the product.

Product Documents for SJF 0661

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SJF 0661

For research use only

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