Active Degraders: Products

"Active Degraders" has 20 results in Products.
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dTAG-13 

Degrades mutant FKBP12F36V fusion proteins; useful alternative to genetic methods for target validation

MZ 1 

(+)-JQ1 based PROTAC that selectively degrades BRD4 in cells

TL 12-186 

Multikinase degrading PROTAC

dBRD9 

Potent and selective BRD9 degrading PROTAC

dBET1 

(+)-JQ1 based PROTAC targeting BET bromodomains, active in vivo

THAL SNS 032 

Potent and selective Cdk9 degrading PROTAC

AT 1 

(+)-JQ1 based PROTAC with selectivity for BRD4

CM 11 

Homo-PROTAC for self-degradation of pVHL30

dTRIM 24 

TRIM24 degrading PROTAC

ZXH 3-26 

Potent and selective BRD4 degrader

TL 13-12 

Selective ALK degrader

TL 13-112 

Selective ALK Degrader

BSJ-03-123 

Selective Cdk6 degrader

VZ 185 

Potent and selective BRD7/9 Degrader

BSJ-04-132 

Selective Cdk4 degrader

BSJ-03-204 

Selective Cdk4/6 degrader

CRBN-6-5-5-VHL 

Potent and selective cereblon degrader; cell-permeable

Thalidomide 4'-ether-PEG3-amine 

Cereblon ligand with PEG linker and terminal amine for onward chemistry

aTAG 2139 

Degrader of MTH1 fusion proteins for use within the aTAG system

aTAG 4531 

Degrader of MTH1 fusion proteins for use within the aTAG system
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