SK 609

Catalog # Availability Size / Price Qty
7039/5
7039/25
SK 609 | CAS No. 1092797-77-7 | Dopamine D3 Receptor Agonists
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Description: Dopamine D3 receptor biased agonist

Chemical Name: 2-chloro-α-methyl-benzenepropanamine hydrochloride

Purity: ≥98%

Product Details
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Biological Activity

SK 609 is a dopamine D3 receptor biased agonist. Preferentially signals via the G protein-dependent pathway (EC50 values for G protein and β-arrestin-dependent signaling are 1.1 and 50.2 μM, respectively). Exhibits selectivity for D3 over D2 receptors. Improves motor deficits in rodent Parkinson's disease models and ameliorates L-DOPA (Cat. No. 3788) induced abnormal involuntary movements.

Technical Data

M.Wt:
220.14
Formula:
C10H14ClN.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1092797-77-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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