Biological Activity Activator of KCa3.1 and KCa2 channels (EC50 values are 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively). Potentiates acetylcholine-induced EDHF-type dilations of mouse carotid arteries and lowers blood pressure in normotensive and hypertensive mice.
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Store at +4°C
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For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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