SKA 31

Catalog # Availability Size / Price Qty
3670/10
3670/50
Ca2+-Activated Potassium Channel Activators Small Molecule
1 Image
Description: Activator of KCa3.1 and KCa2 channels

Chemical Name: Naphtho[1,2-d]thiazol-2-ylamine

Purity: ≥99%

Product Details
Reviews (1)

Biological Activity

Activator of KCa3.1 and KCa2 channels (EC50 values are 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively). Potentiates acetylcholine-induced EDHF-type dilations of mouse carotid arteries and lowers blood pressure in normotensive and hypertensive mice.

Technical Data

M.Wt:
200.26
Formula:
C11H8N2S
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
40172-65-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Reviews for SKA 31

Average Rating: 5 (Based on 1 Review)

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SKA 31 is a great channel activator and works well on biological lab conditions
By Anonymous on 10/13/2018
Species: Human

Great product for studies on Kca channel opening as a measure to compare between other activators. Would use again and suggest to others.


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