SKF 86002 dihydrochloride

Catalog # Availability Size / Price Qty
2008/10
2008/50
SKF 86002 dihydrochloride | CAS No. 116339-68-5 | p38 Inhibitors
1 Image
Description: p38 MAPK inhibitor; anti-inflammatory agent

Chemical Name: 6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo[2,1-b]thiazole dihydrochloride

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

Inhibitor of p38 MAP kinase (IC50 = 0.1 - 1 μM). Potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 μM). Also inhibits 5-lipoxygenase- and cyclooxygenase-mediated arachidonic acid metabolism in RBL-1 cells (IC50 values are 10 and 100 μM respectively). Anti-inflammatory following oral administration in vivo.

Technical Data

M.Wt:
370.27
Formula:
C16H12FN3S.2HCl
Solubility:
Soluble to 50 mM in water
Purity:
≥98%
Storage:
Desiccate at +4°C
CAS No:
116339-68-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citation for SKF 86002 dihydrochloride

The citations listed below are publications that use Tocris products. Selected citations for SKF 86002 dihydrochloride include:

1 Citation: Showing 1 - 1

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for SKF 86002 dihydrochloride

There are currently no reviews for this product. Be the first to review SKF 86002 dihydrochloride and earn rewards!

Have you used SKF 86002 dihydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.