Home / Adrenergic alpha-2 Receptor Antagonists / SKF 86466 hydrochloride

SKF 86466 hydrochloride

3866 1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3866/10
3866/50

15% Off Limited-time Savings on Your Reagents, Assays, and Kits
Now through September 27th, you can save 15% on Bio-Techne reagents, assays, and kits (including Novus, Tocris, and R&D Systems). Use promotion code SAVE15 at checkout on orders over $1,000. See terms and conditions for offer details.

SKF 86466 hydrochloride | CAS No. 86129-54-6 | Adrenergic alpha-2 Receptor Antagonists
1 Image
Description: Potent and selective α2 antagonist

Chemical Name: 6-Chloro-N-methyl-2,3,4,5-tetrahydro-1-H-3-benzazepine hydrochloride

Purity: ≥98%

Product Details
Citations (1)
Supplemental Products
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

SKF 86466 hydrochloride is a potent and selective α2 antagonist at pre- and post-junctional α2-adrenoceptors (Ki values are 13 and 17 nM respectively). Exhibits antihypertensive activity in a rat model.

Technical Data

M.Wt:
232.15
Formula:
C11H14ClN.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
86129-54-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citation for SKF 86466 hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for SKF 86466 hydrochloride include:

1 Citation: Showing 1 - 1

  1. Capturing the biology of disease severity in a PSC-based model of familial dysautonomia.
    Authors: Zeltner Et al.
    Nat Med  2016;22:1421

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

VersaClone cDNA Plasmids

Human ADRA2A (AAF91441) VersaClone cDNA

RDC0256

Human ADRA2B (NP_000673) VersaClone cDNA

RDC0257

Human ADRA2C (NP_000674) VersaClone cDNA

RDC0258

Rat alpha-2A Adrenergic R/ADRA2A (NP_036871) VersaClone cDNA

RDC0818

Reviews for SKF 86466 hydrochloride

There are currently no reviews for this product. Be the first to review SKF 86466 hydrochloride and earn rewards!

Have you used SKF 86466 hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.