SKF 97541

Catalog # Availability Size / Price Qty
SKF 97541 | CAS No. 127729-35-5 | GABA-B Receptor Agonists
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Description: Highly potent GABAB agonist; also GABAA-ρ antagonist
Alternative Names: CGP 35024

Chemical Name: 3-Aminopropyl(methyl)phosphinic acid

Product Details
Citations (8)
Supplemental Products

Biological Activity

SKF 97541 is a potent GABAB agonist (EC50 = 50 nM). SKF 97541 depresses striatal synaptic potentials and hyperpolarizes nigral neurons (EC50 values = 92 nM and 150 nM, respectively). SKF 97541 shows antidepressant effects in animal models and is also a GABAA-ρ antagonist.

Technical Data

Soluble to 100 mM in water
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Citations for SKF 97541

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