SKF 97541

  ( 6 citations )    
Product Datasheet
Catalog Number:0379
Alternate Names:CGP 35024
Chemical Name:3-Aminopropyl(methyl)phosphinic acid
Product Details
Citations (6)
Supplemental Products
Reviews
Biological Activity
Very potent GABAB agonist, at least ten times more active than baclofen (Cat. No. 0417). Also GABAA-ρ antagonist.
Technical Data
  • M.Wt:
    137.12
  • Formula:
    C4H12NO2P
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Desiccate at RT
  • CAS No:
    127729-35-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for SKF 97541 include:

6 Citations: Showing 1 - 6
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  1. FRET-based sensors unravel activation and allosteric modulation of the GABAB receptor.
    Authors: Lecat-Guillet
    Cell Chem Biol  2017;24(3):360
  2. Presynaptic peptidergic modulation of olfactory receptor neurons in Drosophila.
    Authors: Ignell Et al.
    Br J Pharmacol  2009;106:13070
  3. A presynaptic gain control mechanism fine-tunes olfactory behavior.
    Authors: Root Et al.
    Neuron  2008;59:311
  4. Differential regulation of morphine antinociceptive effects by endogenous enkephalinergic system in the forebrain of mice.
    Authors: Chen Et al.
    Mol Pain  2008;4:41
  5. Peripheral GABAB agonists stimulate gastric acid secretion in mice.
    Authors: Piqueras and Martínez
    Br J Pharmacol  2004;142:1038
  6. The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen.
    Authors: Wood Et al.
    Mol Pain  2000;131:1050

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