SKPin C1

  ( 1 citations )    
Product Datasheet
Catalog Number:4817
Chemical Name:2-[4-Bromo-2-[[4-oxo-3-(3-pyridinylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]phenoxy]acetic acid
Product Details
Citations (1)
Reviews
Biological Activity
Inhibitor of Skp2-mediated p27 degradation. Induces p27 accumulation in metastatic melanoma cell lines. Promotes G1/S cell cycle arrest in T47D cells and LNCaP cells; induces G2/M cell cycle arrest in MCF-7 cells.
Technical Data
  • M.Wt:
    465.34
  • Formula:
    C18H13BrN2O4S2
  • Solubility:
    Soluble to 10 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    432001-69-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for SKPin C1 include:

1 Citations: Showing 1 - 1

  1. Proliferation and Survival of Embryonic Sympathetic Neuroblasts by MYCN and Activated ALK Signaling.
    Authors: Kramer Et al.
    J Neurosci  2016;36:10425

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