Biological ActivityProtease-activated receptor 2 (PAR2) agonist (Ki = 9.64 μM and IC50 = 10.4 μM). Corresponds to the tethered ligand exposed by trypsin cleavage of PAR-2.
Control Peptide also available.
(Modifications: Val-6 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2.
Bohm et al.
International union of pharmacology XXVIII. Proteinase-activated receptors.
Hollenberg and Compton
Binding of a highly potent protease-activated receptor-2 (PAR2) activating peptide, [3H]2-furoyl-LIGRL-NH2, to human PAR2.
Kanke et al.
Citation for SLIGKV-NH2
The citations listed below are publications that use Tocris products. Selected citations for SLIGKV-NH2 include:
1 Citation: Showing 1 - 1
Monitoring G protein-coupled receptor and [beta]-arrestin trafficking in live cells using enhanced bystander BRET
Authors: Namkung Et al.
Nature Communications 2016;7:12178
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VersaClone cDNA Plasmids
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