SLIGKV-NH2

Name: SLIGKV-NH2
Brand: Tocris Bioscience
SKU: 3010
Price: 229 USD
Availability: InStock

Tocris Bioscience | Catalog # 3010

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Citations (22)

Product Documents

PAR2 receptor agonist

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

PAR2 receptor agonist

View all Protease-Activated Receptor Agonists »

Product Description

SLIGKV-NH2 is a protease-activated receptor 2 (PAR₂) agonist (K_i = 9.64 μM and IC₅₀ = 10.4 μM). Corresponds to the tethered ligand exposed by trypsin cleavage of PAR-2.

Control Peptide also available.

Product Specifications for SLIGKV-NH2

Molecular Weight

614.78

Formula

C₂₈H₅₄N₈O₇

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

190383-13-2

PubChem ID

10483914

InChI Key

HOWDUIVVWDUEED-WAUHAFJUSA-N

SMILES

[H]N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in water

Calculators

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

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g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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Concentration 1 (C1)

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Concentration 2 (C2)

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The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Desired Reconstitution Concentration

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 22 publications citing the usage of this product.

Hollenberg and Compton International union of pharmacology XXVIII. Proteinase-activated receptors. Pharmacol.Rev. 2002 PMID: 12037136
Kanke Binding of a highly potent protease-activated receptor-2 (PAR2) activating peptide, [³H]2-furoyl-LIGRL-NH₂, to human PAR2. Br.J.Pharmacol. 2005 PMID: 15765104
Bohm Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2. Biochem.J. 1996 PMID: 8615752

Product Documents for SLIGKV-NH2

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for SLIGKV-NH2

For research use only

Citations for SLIGKV-NH2

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