Catalog Number: 3010
Biological Activity
Protease-activated receptor 2 (PAR2) agonist (Ki = 9.64 μM and IC50 = 10.4 μM). Corresponds to the tethered ligand exposed by trypsin cleavage of PAR-2. Control peptide VKGILS-NH2 also available (Cat. No. 3392).
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: Val-6 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2.
    Bohm et al.
    Biochem.J., 1996;314:1009
  2. International union of pharmacology XXVIII. Proteinase-activated receptors.
    Hollenberg and Compton
    Pharmacol.Rev., 2002;54:203
  3. Binding of a highly potent protease-activated receptor-2 (PAR2) activating peptide, [3H]2-furoyl-LIGRL-NH2, to human PAR2.
    Kanke et al.
    Br.J.Pharmacol., 2005;145:255

The citations listed below are publications that use Tocris products. Selected citations for SLIGKV-NH2 include:

Showing Results 1 - 1 of 1

  1. Monitoring G protein-coupled receptor and [beta]-arrestin trafficking in live cells using enhanced bystander BRET
    Authors: Namkung Et al.
    Nature Communications
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