SLIGRL-NH2

  ( 5 citations )    
Product Datasheet
Catalog Number:1468
Chemical Name:
Product Details
Citations (5)
Supplemental Products
Reviews
Biological Activity
Agonist peptide derived from the N-terminus of protease-activated receptor-2 (PAR2). Activates PAR2 (EC50 ~ 5 μM) and facilitates gastrointestinal transit in mice in vivo.

Control Peptide also available.

Technical Data
  • M.Wt:
    656.82
  • Formula:
    C29H56N10O7
  • Sequence:
    SLIGRL

    (Modifications: Leu-6 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    171436-38-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for SLIGRL-NH2 include:

5 Citations: Showing 1 - 5
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  1. Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells.
    Authors: Tripathi Et al.
    Invest Ophthalmol Vis Sci  2014;55:3912
  2. Protease activated receptor-2 contributes to heart failure.
    Authors: Antoniak Et al.
    EMBO J  2013;8:e81733
  3. TRPV1-lineage neurons are required for thermal sensation.
    Authors: Mishra Et al.
    PLoS One  2011;30:582
  4. Protease activated receptors 1 and 4 sensitize TRPV1 in nociceptive neurones.
    Authors: Vellani Et al.
    Mol Pain  2010;6:61
  5. Activation of protease-activated receptors 3 and 4 accelerates tissue factor-induced thrombin generation on the surface of vascular smooth muscle cells.
    Authors: Vidwan Et al.
    Arterioscler Thromb Vasc Biol  2010;30:2587

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