Catalog Number: 1468
Biological Activity
Agonist peptide derived from the N-terminus of protease-activated receptor-2 (PAR2). Activates PAR2 (EC50 ~ 5 μM) and facilitates gastrointestinal transit in mice in vivo. Control peptide LRGILS-NH2 (Cat. No. 3394) also available.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: Leu-6 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Detection of functional receptors for the proteinase-activated-receptor-2-activating polypeptide, SLIGRL-NH2, in rat vascular and gastric smooth muscle.
    Al-Ani et al.
    Can.J.Physiol.Pharmacol., 1995;73:1203
  2. In vivo evidence that protease-activated receptors 1 and 2 modulate gastrointestinal transit in the mouse.
    Kawabata et al.
    Br.J.Pharmacol., 2001;133:1213
  3. Molecular cloning of a potential proteinase activated receptor.
    Nystedt et al.
    Proc.Natl.Acad.Sci.U.S.A., 1994;91:9208
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