Biological ActivityLRGILS-NH2 is a reversed amino acid sequence control peptide for SLIGRL-NH2, a protease-activated receptor-2 (PAR2) agonist that facilitates gastrointestinal transit in vivo.
Active Analog also available.
(Modifications: Ser-6 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Evidence that PAR-1 and PAR-2 mediate prostanoid-dependent contraction in isolated guinea-pig gallbladder.
Tognetto et al.
Protease-activated receptor-2 (PAR-2)-related peptides induce tear secretion in Rats: Involvement of PAR-2 and non-PAR-2 mechanisms.
Nishikawa et al.
Initial support for the hypothesis that PAR2 is involved in the immune response to Nippostrongylus brasiliensis in mice.
Devlin et al.
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VersaClone cDNA Plasmids
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Was used in an in-vitro stimulation assay as a control peptide