SLU-PP-332

Key Product Details

Product Description

SLU-PP-332 is a potent and selective pan estrogen related receptor (ERR) agonist (EC₅₀ values are 98 nM, 230 nM and 430 nM for ERRα, ERRβ and ERRγ respectively). In a mouse model of metabolic syndrome SLU-PP-332 increases energy expenditure and fatty acid oxidation, decreases fat mass, and improves insulin sensitivity. Also increases mitochondrial respiration in vitro.

Product Specifications for SLU-PP-332

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for SLU-PP-332

The following data is based on the product molecular weight 290.32.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.44 mL	17.22 mL	34.44 mL
5 mM	0.69 mL	3.44 mL	6.89 mL
10 mM	0.34 mL	1.72 mL	3.44 mL
50 mM	0.07 mL	0.34 mL	0.69 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Billon A synthetic ERR agonist alleviates metabolic syndrome. J.Pharmacol.Exp.Ther. 2024 PMID: 37739806
• Billon Synthetic ERRα/β/γ agonist induces an ERRα-dependent acute aerobic exercise response and enhances exercise capacity. ACS Chem.Biol. 2023 PMID: 36988910

Product Documents for SLU-PP-332