SmarcAL1 Recombinant Enzymes

Novus Biologicals | Catalog # NBP3-48884

Novus Biologicals
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Key Product Details

Source

Sf 9 (baculovirus)
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Product Specifications

Description

Human HARP (aa 2-953) fused to 6xHis and FLAG-tag at the N-terminus. (Uniprot: Q9NZC9)

Purity

Immunogen affinity purified

Protein / Peptide Type

Recombinant Enzymes

Formulation, Preparation, and Storage

NBP3-48884
Formulation 20 mM Tris-HCl, pH 7.9, 150 mM NaCl, 15% glycerol, 2 mM MgCl2, 0.2 mM EDTA, 1 mM DTT, 10 mM beta-glycerophospate, 0.4 mM PMSF, 1 mM benzamidine and 0.4 mg/ml recombinant human insulin
Preservative No Preservative
Concentration Please see the vial label for concentration. If unlisted please contact technical services.
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -80C. Avoid freeze-thaw cycles.

Background: SmarcAL1

SmarcAL1 is encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.

Alternate Names

ATP-driven annealing helicase, EC 3.6.1, EC 3.6.4.-, HARPSWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A-like protein 1, HepA-related protein, HHARP, SIOD, SMARCA-like protein 1, subfamily a-like 1, Sucrose nonfermenting protein 2-like 1, SWI/SNF related, matrix associated, actin dependent regulator of chromatin

Gene Symbol

SMARCAL1

Additional SmarcAL1 Products

Product Documents for SmarcAL1 Recombinant Enzymes

Certificate of Analysis

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Product Specific Notices for SmarcAL1 Recombinant Enzymes

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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