SNC 80

Catalog # Availability Size / Price Qty
SNC 80 | CAS No. 156727-74-1 | delta Opioid Receptor Agonists
1 Image
Description: Highly selective non-peptide δ agonist

Chemical Name: (+)-4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide

Purity: ≥98%

Product Details
Citations (18)
Supplemental Products

Biological Activity

SNC 80 is a highly selective and potent non-peptide δ-opioid agonist, 2000-fold selective over μ-opioid receptors.

Technical Data

Soluble to 100 mM in 1eq. HCl with gentle warming and to 20 mM in DMSO
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Molarity Calculator


*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for SNC 80

The citations listed below are publications that use Tocris products. Selected citations for SNC 80 include:

18 Citations: Showing 1 - 10

  1. Critical Role for Gi/o-Protein Activity in the Dorsal Striatum in the Reduction of Voluntary Alcohol Intake in C57Bl/6 Mice.
    Authors: Robins Et al.
    Front Psychiatry  2018;9:112
  2. Functional Divergence of Delta and Mu Opioid Receptor Organization in CNS Pain Circuits.
    Authors: Wang Et al.
    Neuron  2018;98:90
  3. Alterations in opioid inhibition cause widespread nociception but do not affect anxiety-like behavior in oral cancer mice.
    Authors: Ye
    Neuroscience  2017;363:50
  4. A Broad G Protein-Coupled Receptor Internalization Assay that Combines SNAP-Tag Labeling, Diffusion-Enhanced Resonance Energy Transfer, and a Highly Emissive Terbium Cryptate.
    Authors: Levoye Et al.
    Brain Struct Funct  2015;6:167
  5. A μ-δ opioid receptor brain atlas reveals neuronal co-occurrence in subcortical networks.
    Authors: Erbs Et al.
    J Neurosci  2015;220:677
  6. Ligand requirements for involvement of PKCη in synergistic analgesic interactions between spinal μ and δ opioid receptors.
    Authors: Schuster Et al.
    Transl Oncol  2015;172:642
  7. Prolonged mor. treatment alters δ opioid receptor post-internalization trafficking.
    Authors: Ong Et al.
    Front Endocrinol (Lausanne)  2015;172:615
  8. The δ-opioid receptor affects epidermal homeostasis via ERK-dependent inhibition of transcription factor POU2F3.
    Authors: Neumann Et al.
    J Invest Dermatol  2015;135:471
  9. δ-Opioid receptor agonists inhibit migraine-related hyperalgesia, aversive state and cortical spreading depression in mice.
    Authors: Pradhan Et al.
    Br J Pharmacol  2014;171:2375
  10. Anti-analgesic effect of the mu/delta opioid receptor heteromer revealed by ligand-biased antagonism.
    Authors: Milan-Lobo Et al.
    PLoS One  2013;8:e58362


No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for SNC 80

There are currently no reviews for this product. Be the first to review SNC 80 and earn rewards!

Have you used SNC 80?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.