SODD/BAG4 Antibody [DyLight 680]

Name: SODD/BAG4 Antibody [DyLight 680]
Brand: Novus Biologicals
SKU: AF4349Y
Price: 549 USD
Availability: InStock

Novus Biologicals | Catalog # AF4349Y

Submit a review

Product Documents

View Available Conjugates

100% Guarantee

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Mouse, Rat

Applications

Knockout Validated, Western Blot

Label

DyLight 680 (Excitation = 692 nm, Emission = 712 nm)

Antibody Source

Polyclonal Goat IgG

View all SODD/BAG4 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant mouse SODD/BAG4
Met1-Leu457
Accession # Q8CI61

Specificity

Detects endogenous mouse and rat SODD/BAG4 in Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for SODD/BAG4 Antibody [DyLight 680]

Application

Recommended Usage

Knockout Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: SODD/BAG4

Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, DR5, and DR6 were recently identified. Cell death signal is transduced by death domain containing adapter molecules through the interaction with death domain of these death receptors. A novel TNF-R1 interacting protein was recently identified and designated SODD for silencer of death domains. SODD associates with the death domain of TNF-R1 and prevents constitutive activation of TNF-R1 signaling. TNF treatment releases SODD and permits adapter molecules such as TRADD recruiting to the active TNF-R1 complex, which activates TNF signaling pathways. SODD also interacts with DR3. SODD is ubiquitously expressed in human tissues and cell lines.

Long Name

Silencer of Death Domains

Alternate Names

BAG4

Gene Symbol

BAG4

Additional SODD/BAG4 Products

Product Documents for SODD/BAG4 Antibody [DyLight 680]

Download Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for SODD/BAG4 Antibody [DyLight 680]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Apoptosis Adaptor Proteins

Customer Reviews for SODD/BAG4 Antibody [DyLight 680]

There are currently no reviews for this product. Be the first to review SODD/BAG4 Antibody [DyLight 680] and earn rewards!

Have you used SODD/BAG4 Antibody [DyLight 680]?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image