Somatostatin R3/SSTR3 Antibody (S08-2G8)

Novus Biologicals | Catalog # NBP3-19777

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S08-2G8 expressed in HEK293
View all Somatostatin R3/SSTR3 Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human Somatostatin R3/SSTR3 (Uniprot # P32745)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Somatostatin R3/SSTR3 Antibody (S08-2G8)

Western Blot: Somatostatin R3/SSTR3 Antibody (S08-2G8) [NBP3-19777]

Western Blot: Somatostatin R3/SSTR3 Antibody (S08-2G8) [NBP3-19777]

Western Blot: Somatostatin R3/SSTR3 Antibody (S08-2G8) [NBP3-19777] - Western blot detection of Somatostatin R3/SSTR3 in Jurkat cell lysates using NBP3-19777 (1:500 diluted). Predicted band size: 46kDa. Observed band size: 46kDa.

Applications for Somatostatin R3/SSTR3 Antibody (S08-2G8)

Application
Recommended Usage

Western Blot

1/2000-1/10000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Somatostatin R3/SSTR3

Expression of Somatostatin Receptor Type 3 (SSTR3) has been reported in brain, breast, eye, gastrointestinal tract, pancreas, and thyroid. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This "turn-off" activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates. Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Long Name

Somatostatin Receptor Type 3

Alternate Names

SomatostatinR3, SSR-28, SST3, SSTR3

Gene Symbol

SSTR3

Additional Somatostatin R3/SSTR3 Products

Product Documents for Somatostatin R3/SSTR3 Antibody (S08-2G8)

Certificate of Analysis

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Product Specific Notices for Somatostatin R3/SSTR3 Antibody (S08-2G8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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