Sphingosine-1-phosphate

  ( 4 citations )    
Product Datasheet
Catalog Number:1370
Chemical Name:(E)-D-erythro-2-amino-1-(dihydrogenphosphate)-4-octadecene-1,3-diol
Product Details
Citations (4)
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Biological Activity
Endogenous second messenger involved in the control of cell proliferation and motility, and Ca2+ mobilization. Acts as an agonist at sphingosine-1-phosphate receptors (S1P1-5) and as an activator of GPR3, GPR6 and GPR12. Effectors regulated include p38 MAP kinase, PLC, adenylyl cyclase, myosin light chain phosphatase and focal adhesion kinase.
Technical Data
  • M.Wt:
    379.48
  • Formula:
    C18H38NO5P
  • Purity:
    >98
  • Storage:
    Desiccate at +4°C
  • CAS No:
    26993-30-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Sphingosine-1-phosphate include:

4 Citations: Showing 1 - 4
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  1. Application of xCELLigence RTCA Biosensor Technology for Revealing the Profile and Window of Drug Responsiveness in Real Time.
    Authors: Kho Et al.
    Mol Pain  2015;5:199
  2. Lysophosphatidic acid mediates myeloid differentiation within the human bone marrow microenvironment.
    Authors: Evseenko Et al.
    PLoS One  2013;8:e63718
  3. Identification of the C3a receptor (C3AR1) as the target of the VGF-derived peptide TLQP-21 in rodent cells.
    Authors: Hannedouche Et al.
    Biosensors (Basel)  2013;288:27434
  4. PAM mediates sustained inhibition of cAMP signaling by sphingosine-1-phosphate.
    Authors: Pierre Et al.
    EMBO J  2004;23:3031

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