SR 1078

Tocris Bioscience | Catalog # 4874

RORα/γ agonist
Tocris Bioscience

Key Product Details

Description

RORα/γ agonist
View all ROR/NR1F Agonists »

Product Description

SR 1078 is an agonist of retinoic acid receptor-related orphan receptors (ROR) RORα/γ. Increases transcription of RORα target genes; thought to increase p53 stability.

Licensing Information

Sold under license from The Scripps Research Institute.

Product Specifications for SR 1078

Molecular Weight

431.25

Formula

C17H10F9NO2

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4-(trifluoromethyl)benzamide

CAS Number

1246525-60-9

PubChem ID

17980288

InChI Key

DUXWIYXHHGNUJU-UHFFFAOYSA-N

SMILES

OC(C(F)(F)F)(C(F)(F)F)C(C=C1)=CC=C1NC(C2=CC=C(C(F)(F)F)C=C2)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 43.12 100
Ethanol 43.12 100

Preparing Stock Solutions for SR 1078

The following data is based on the product molecular weight 431.25.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.32 mL 11.59 mL 23.19 mL
5 mM 0.46 mL 2.32 mL 4.64 mL
10 mM 0.23 mL 1.16 mL 2.32 mL
50 mM 0.05 mL 0.23 mL 0.46 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 12 publications citing the usage of this product.

Product Documents for SR 1078

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SR 1078

For research use only

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