Chemical Name:[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-phosphonic acid tetraethyl ester
Biological Activity Pregnane X receptor (PXR) agonist (EC50 values are 200 and 700 nM for human and rabbit PXR respectively). Activates the farnesoid X receptor (FXR) at μM concentrations. Displays hypocholesterolaemic activity via enchanced degradation of HMG-CoA reductase.
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Store at +4°C
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For batch specific data refer to the Certificate of Analysis.
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