4 nAChR antagonist (IC50
= 10.2 μ
M). Selectively binds α
4 over α
2 and α
7 subtypes (Ki
values are 0.508, >100 and >100 μ
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Novel α3β4 nicotinic acetylcholine receptor-selective ligands. Discovery, structure-activity studies, and pharmacological evaluation.
Zaveri et al.