SR 16584

Key Product Details

Product Description

SR 16584 is a selective α3β4 nAChR antagonist (IC₅₀ = 10.2 μM). Selectively binds α3β4 over α4β2 and α7 subtypes (K_i values are 0.508, >100 and >100 μM, respectively).

Product Specifications for SR 16584

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for SR 16584

The following data is based on the product molecular weight 270.37.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.70 mL	18.49 mL	36.99 mL
5 mM	0.74 mL	3.70 mL	7.40 mL
10 mM	0.37 mL	1.85 mL	3.70 mL
50 mM	0.07 mL	0.37 mL	0.74 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

• Zaveri Novel α3β4 nicotinic acetylcholine receptor-selective ligands. Discovery, structure-activity studies, and pharmacological evaluation. J.Med.Chem. 2012 PMID: 20979364

Product Documents for SR 16584