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SR 2640 hydrochloride

Catalog #: 1804
1 Citation Datasheet / COA / SDS

Discontinued Product

1804 has been discontinued.
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SR 2640 hydrochloride | CAS No. 146662-42-2 | Leukotriene and Related Receptor Antagonists
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Description: Potent, selective LTD4 /LTE4 receptor antagonist

Chemical Name: 2-[[3-(2-Quinolinylmethoxy)phenyl]amino]benzoic acid hydrochloride

Purity: ≥99%

Product Details
Citations (1)
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Biological Activity

SR 2640 hydrochloride is a potent and selective competitive leukotriene D4 and E4 receptor antagonist. Inhibits LTD4- but not histamine-induced guinea pig ileum and trachea contraction (pA2 = 8.7). Also inhibits LTD4-attenuation of human PMN chemotaxis. Orally active in vivo.

Technical Data

M.Wt:
406.87
Formula:
C23H18N2O3.HCl
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
146662-42-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for SR 2640 hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for SR 2640 hydrochloride include:

1 Citation: Showing 1 - 1

  1. Pranlukast is a novel small molecule activator of the two-pore domain potassium channel TREK2.
    Authors: Wright Et al.
    Biochem Biophys Res Commun  2019;520:35

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