SR 33805 oxalate

Catalog # Availability Size / Price Qty
1806/10
SR 33805 oxalate | CAS No. 121346-33-6 | Cav1.x Channel Blockers
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Description: CaV1.x blocker; binds allosterically to distinct site

Chemical Name: 3,4-Dimethoxy-N-methyl-N-[3-[4-[[1-methyl-3-(1-methylethyl)-1H-indol-2-yl]sulfonyl]phenoxy]propyl]benzeneethanamine

Purity: ≥99%

Product Details
Citations (1)
Reviews

Biological Activity

Potent Ca2+ channel antagonist; binds allosterically to the a1-subunit of L-type Ca2+ channels (Kd = 20 pM), at a site distinct from other types of blocker. Shows some selectivity for vascular smooth muscle, inducing vasorelaxation without producing inotropic or chronotropic effects. Inhibits PDGF-stimulated smooth muscle cell proliferation.

Technical Data

M.Wt:
654.77
Formula:
C32H40N2O5S.C2H2O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
121346-33-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for SR 33805 oxalate

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