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SRPIN340

5063 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
5063/10
5063/50

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SRPIN340 | CAS No. 218156-96-8 | Other Kinase Inhibitors
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Description: Selective SRPK1 inhibitor

Chemical Name: N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide

Purity: ≥98%

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Biological Activity

SRPIN340 is a selective serine arginine protein kinase (SRPK) 1 inhibitor (Ki = 0.89 μM). Inhibits SRPK2 at higher concentrations. Does not significantly inhibit other SRPKs such as CLK1 and CLK4, or other classes of SR kinases. Down-regulates expression of VEGF165 but does not affect VEGF165b expression.

Technical Data

M.Wt:
349.35
Formula:
C18H18F3N3O
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in 1eq. HCl
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
218156-96-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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