SRPIN340

Catalog # Availability Size / Price Qty
5063/10
5063/50
Cat.No. 5063 - SRPIN340 | C18H18F3N3O | CAS No. 218156-96-8
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Description: Selective SRPK1 inhibitor

Chemical Name: N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide

Purity: ≥98%

Product Details
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Biological Activity

Selective serine arginine protein kinase (SRPK) 1 inhibitor (Ki = 0.89 μM). Inhibits SRPK2 at higher concentrations. Does not significantly inhibit other SRPKs such as CLK1 and CLK4, or other classes of SR kinases. Down-regulates expression of VEGF165 but does not affect VEGF165b expression.

Technical Data

M.Wt:
349.35
Formula:
C18H18F3N3O
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in 1eq. HCl
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
218156-96-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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