STOCK2S 26016

Catalog # Availability Size / Price Qty
5570/10
5570/50
Cat.No. 5570 - STOCK2S 26016 | C20H19N3O2 | CAS No. 332922-63-1
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Description: Lysine deficient protein kinase (WNK) signaling inhibitor

Chemical Name: 7-Ethoxy-N3-(2-furanylmethyl)-3,9-acridinediamine

Purity: ≥98%

Product Details
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Biological Activity

Lysine deficient protein kinase (WNK) signaling inhibitor (IC50 = 16 μM). Inhibits binding of WNK1 and WNK4 to SPAK and phosphorylation of downstream transporters, NKCC1 and NCC, in mouse vascular smooth muscle and distal convoluted tubule cell cultures exposed to hypotonic shock, respectively.

Technical Data

M.Wt:
333.38
Formula:
C20H19N3O2
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
332922-63-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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