Catalog Number: 1621
Alternate Names: Streptozotocin
Chemical Name: 2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-D-glucose
Biological Activity
Antibiotic and antitumor agent. Alkylates DNA and induces diabetes mellitus via reduction of nicotinamide adenine dinucleotide in pancreatic β-cells in vivo.
Technical Data
  • M.Wt:
    265.22
  • Formula:
    C8H15N3O7
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
    >95%
  • Storage:
    Store at -20°C
  • CAS No:
    18883-66-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Alkylation of DNA in rat tissues following administration of streptozotocin.
    Bennett and Pegg
    Cancer Res., 1981;41:2786
  2. Steptozotocin: A review of its pharmacology, efficacy and toxicity.
    Weis
    Cancer Treat. Rep., 1982;66:427

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