Chemical Name: 2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-D-glucose
Biological ActivityStreptozocin is an antibiotic and antitumor agent. Alkylates DNA and induces diabetes mellitus via reduction of nicotinamide adenine dinucleotide in pancreatic β-cells in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Alkylation of DNA in rat tissues following administration of streptozotocin.
Bennett and Pegg
Cancer Res., 1981;41:2786
Steptozotocin: A review of its pharmacology, efficacy and toxicity.
Cancer Treat. Rep., 1982;66:427
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