Streptozocin

Tocris Bioscience | Catalog # 1621

DNA alkylator; antitumor and induces diabetes
Tocris Bioscience

Key Product Details

Description

DNA alkylator; antitumor and induces diabetes

Alternative Names

Streptozotocin
View all Apoptosis Inducer Compounds »

Product Description

Streptozocin is an antibiotic and antitumor agent. Alkylates DNA and induces diabetes mellitus via reduction of nicotinamide adenine dinucleotide in pancreatic β-cells in vivo.

Product Specifications for Streptozocin

Molecular Weight

265.22

Formula

C8H15N3O7

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-D-glucose

CAS Number

18883-66-4

PubChem ID

2733335

InChI Key

ZSJLQEPLLKMAKR-YDEIVXIUSA-N

SMILES

O[C@H]1[C@H](O)[C@@H](CO)OC(O)[C@@H]1NC(N(C)N=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 26.52 100
DMSO 26.52 100

Preparing Stock Solutions for Streptozocin

The following data is based on the product molecular weight 265.22.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.77 mL 18.85 mL 37.70 mL
5 mM 0.75 mL 3.77 mL 7.54 mL
10 mM 0.38 mL 1.89 mL 3.77 mL
50 mM 0.08 mL 0.38 mL 0.75 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 15 publications citing the usage of this product.

Product Documents for Streptozocin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Streptozocin

For research use only

⚠ WARNING: This product can expose you to chemicals including Streptozocin (streptozotocin), which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Customer Reviews for Streptozocin (1)

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  • Streptozocin used on GLUT2 positive neuroendocrine tumor cells
    Name: Anonymous
    Species: Human
    Cell Line/Tissue: GLUT2 positive neuroendocrine tumor cells
    Verified Customer | Posted 02/18/2019
    Streptozocin used on GLUT2 positive neuroendocrine tumor cells.Streptozocin was used to induce type 1 diabetes
    Streptozocin 1621

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