Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Biotin

Antibody Source

Polyclonal Goat IgG
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Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Sulfatase Modifying Factor 2/SUMF2
Gln26-Leu301
Accession # Q8NBJ7

Specificity

Detects human Sulfatase Modifying Factor 2/SUMF2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 45% cross-reactivity with recombinant mouse SUMF2 is observed and less than 1% cross-reactivity with recombinant human SUMF1 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Sulfatase Modifying Factor 2/SUMF2 Antibody [Biotin]

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Sulfatase Modifying Factor 2/SUMF2

The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternate Names

FGE2

Gene Symbol

SUMF2

Additional Sulfatase Modifying Factor 2/SUMF2 Products

Product Documents for Sulfatase Modifying Factor 2/SUMF2 Antibody [Biotin]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Sulfatase Modifying Factor 2/SUMF2 Antibody [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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