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Sulprostone

Catalog #: 3049
1 Citation Datasheet / COA / SDS
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3049/1
Sulprostone | CAS No. 60325-46-4 | Prostanoid Receptor Agonists
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Description: EP3 and EP1 receptor agonist

Chemical Name: (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3R)-3-hydroxy-4-buten-1-yl]-5-oxocyclopentyl]-N-(methylsulfonyl)-5-heptenamide

Product Details
Citations (1)
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Biological Activity

Sulprostone is a selective EP3 and EP1 receptor agonist (Ki values are 0.6 and 21 nM respectively). Synthetic PGE2 analog and allodynic agent.

Technical Data

M.Wt:
465.56
Formula:
C23H31NO7S
Solubility:
Soluble in methyl acetate (supplied pre-dissolved - 5mg/ml)
Storage:
Store at -20°C
CAS No:
60325-46-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Transient allodynia pain models in mice for assessment of analgesic activity.
    Gil et al.
    Br.J.Pharmacol., 2008;153:769
  2. Prostanoid receptors: Structures, properties, and functions.
    Narumiya et al.
    Phys.Rev., 1999;79:1193

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Citation for Sulprostone

The citations listed below are publications that use Tocris products. Selected citations for Sulprostone include:

1 Citation: Showing 1 - 1

  1. Prostaglandin E2 receptor 3 signaling is induced in placentas with unexplained recurrent pregnancy losses.
    Authors: Ye Et al.
    Endocr Connect  2018;7:749

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