Catalog Number: 3049
Chemical Name: (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3R)-3-hydroxy-4-buten-1-yl]-5-oxocyclopentyl]-N-(methylsulfonyl)-5-heptenamide
Biological Activity
Selective EP3 and EP1 receptor agonist (Ki values are 0.6 and 21 nM respectively). Synthetic PGE2 analog and allodynic agent.
Technical Data
  • M.Wt:
    465.56
  • Formula:
    C23H31NO7S
  • Solubility:
    Soluble in methyl acetate (supplied pre-dissolved - 5mg/ml)
  • Storage:
    Store at -20°C
  • CAS No:
    60325-46-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Transient allodynia pain models in mice for assessment of analgesic activity.
    Gil et al.
    Br.J.Pharmacol., 2008;153:769
  2. Prostanoid receptors: Structures, properties, and functions.
    Narumiya et al.
    Phys.Rev., 1999;79:1193

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