Chemical Name: (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3R)-3-hydroxy-4-buten-1-yl]-5-oxocyclopentyl]-N-(methylsulfonyl)-5-heptenamide
Biological ActivitySulprostone is a selective EP3 and EP1 receptor agonist (Ki values are 0.6 and 21 nM respectively). Synthetic PGE2 analog and allodynic agent.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Transient allodynia pain models in mice for assessment of analgesic activity.
Gil et al.
Prostanoid receptors: Structures, properties, and functions.
Narumiya et al.
Citation for Sulprostone
The citations listed below are publications that use Tocris products. Selected citations for Sulprostone include:
1 Citation: Showing 1 - 1
Prostaglandin E2 receptor 3 signaling is induced in placentas with unexplained recurrent pregnancy losses.
Authors: Ye Et al.
Endocr Connect 2018;7:749
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VersaClone cDNA Plasmids
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