= 9 nM). Also inhibits p38β
and JNK-2 (IC50
values are 90 nM and 100 nM respectively). Displays no significant activity at p38γ
, ERK-2 and JNK-1.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
MAP kinase p38 inhibitors: clinical results and an intimate look at their interactions with p38α protein.
Lee and Dominguez