Chemical Name: 6-Chloro-5-[[4-[(4-fluorophenyl)methyl]-1-piperidinyl]carbonyl-N,N,1-trimethyl-α-oxo-1H-indole-3-acetamide
Biological ActivityPotent p38α inhibitor (IC50 = 9 nM). Also inhibits p38β and JNK-2 (IC50 values are 90 nM and 100 nM respectively). Displays no significant activity at p38γ, p38δ, ERK-2 and JNK-1.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
MAP kinase p38 inhibitors: clinical results and an intimate look at their interactions with p38α protein.
Lee and Dominguez
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for SX 011
There are currently no reviews for this product. Be the first to review SX 011 and earn rewards!
Have you used SX 011?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image