T 112

Key Product Details

Product Description

T 112 is an estrogen-related receptor gamma (ERR&#947) agonist. Promotes maturation of hiPSC-derived cardiomyocytes. T 112 accelerates metabolic and sarcomere maturation in cardiomyocytes, as well as maturation of contractile and electrophysiological properties and ultrastructure organization, when used alone or in combination with other small molecules.

Licensing Information

Sold under license from Orizuru Therapeutics

Product Specifications for T 112

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for T 112

The following data is based on the product molecular weight 489.37.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.43 mL	102.17 mL	204.34 mL
0.5 mM	4.09 mL	20.43 mL	40.87 mL
1 mM	2.04 mL	10.22 mL	20.43 mL
5 mM	0.41 mL	2.04 mL	4.09 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Miki ERRγ enhances cardiac maturation with T-tubule formation in human iPSC-derived cardiomyocytes. Nat.Commun. 2021 PMID: 34155205

Product Documents for T 112