t-TUCB

Catalog # Availability Size / Price Qty
6757/5
Hydrolase Inhibitors Small Molecule
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Description: Potent soluble epoxide hydrolase (sEH) Inhibitor; anti-inflammatory and antinociceptive

Chemical Name: 4-[[trans-4-[[[[4-(Trifluoromethoxy)phenyl]amino]carbonyl]amino]cyclohexyl]oxy]benzoic acid

Purity: ≥98%

Product Details
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Biological Activity

Potent soluble epoxide hydrolase (sEH) Inhibitor (IC50 = 0.9 nM). Enhances hepatic eNOS phosphorylation and NO release. Exhibits antihypertensive and cardioprotective actions in cirrhotic rat models. Suppress the activation of HSCs and reduce hepatic fibrosis through inhibition of NF-κB/IκBα signaling. Anti-inflammatory and antinociceptive.

Technical Data

M.Wt:
438.4
Formula:
C21H21F3N2O5
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
948304-40-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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