Biological Activity Inhibitor of p38 MAPK (IC50 = 7.1 nM for p38 MAPKα). Also inhibits Wnt-3a-stimulated β-catenin signaling. Inhibits 22 kinases by more than 80%, including CK1δ/ε. Anti-inflammatory and anti-rheumatoid arthritis agent. Orally bioavailable.
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Store at +4°C
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For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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