TAK 715

Catalog # Availability Size / Price Qty
4254/10
4254/50
p38 Inhibitors Small Molecule
1 Image
Description: Potent p38 MAPK inhibitor; anti-inflammatory

Chemical Name: N-[4-[2-Ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]benzamide

Purity: ≥99%

Product Details
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Biological Activity

Inhibitor of p38 MAPK (IC50 = 7.1 nM for p38 MAPKα). Also inhibits Wnt-3a-stimulated β-catenin signaling. Inhibits 22 kinases by more than 80%, including CK1δ/ε. Anti-inflammatory and anti-rheumatoid arthritis agent. Orally bioavailable.

Technical Data

M.Wt:
399.51
Formula:
C24H21N3OS
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
303162-79-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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