Tapasin Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-37749

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Tapasin Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide derived from the sequence of human Tapasin

Reactivity Notes

Weakly cross-reacts with bovine Tapasin.

Specificity

Tapasin

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Tapasin Antibody - BSA Free

Western Blot: Tapasin Antibody [NBP2-37749]

Western Blot: Tapasin Antibody [NBP2-37749]

Western Blot: Tapasin Antibody [NBP2-37749] - Western blot analysis of Tapasin, PAb: Lane 1: MW marker, Lane 2: A431 Lysate

Applications for Tapasin Antibody - BSA Free

Application
Recommended Usage

Immunoprecipitation

1:100

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS and 50% Glycerol

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Tapasin

This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Alternate Names

NGS17, TAP Binding Protein, TAPA, TAPBP, TPN, TPSN

Entrez Gene IDs

6892 (Human); 21356 (Mouse); 25217 (Rat)

Gene Symbol

TAPBP

Additional Tapasin Products

Product Documents for Tapasin Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Tapasin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

T Cell Antigen Recognition

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