TC-DAPK 6

Key Product Details

Product Description

TC-DAPK 6 is a potent and selective, ATP-competitive inhibitor of death-associated protein kinase 1 (DAPK1) (IC₅₀ values are 69 and 225 nM for DAPK1 and DAPK3 respectively, when assayed with 10 μM ATP). Displays selectivity for DAPK1 over a range of 48 other kinases, including Abl, AMPK, Chk1, Met and Src (IC₅₀ > 10 μM).

Product Specifications for TC-DAPK 6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for TC-DAPK 6

The following data is based on the product molecular weight 276.29.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	7.24 mL	36.19 mL	72.39 mL
2.5 mM	1.45 mL	7.24 mL	14.48 mL
5 mM	0.72 mL	3.62 mL	7.24 mL
25 mM	0.14 mL	0.72 mL	1.45 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

• Okamoto Identification of death-associated protein kinases inhibitors using structure-based virtual screening. J.Med.Chem. 2009 PMID: 19877644

Product Documents for TC-DAPK 6