Selective histone demethylase KDM2/7 subfamily inhibitor (IC50
values are 0.2, 1.2, 6.8, 55, 83, >100 and >120 μ
M for KDM7A, KDM7B, KDM2A, KDM5A, KDM4C, KDM6A and KDM4A respectively). Inhibits growth of HeLa and KYSE-150 cancer cells in vitro
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Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity.
Suzuki et al.