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TC E3 5032

Catalog #: 6628 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6628/100
TC E3 5032 | CAS No. 835616-60-9 | Degrader Building Blocks
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Description: Precursor to Pomalidomide-based PROTACs

Chemical Name: 2-(2,6-Dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione

Purity: ≥98%

Product Details
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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

TC E3 5032 is a functionalized cereblon ligand for PROTAC® research and development. Precursor to Pomalidomide (Cat.No. 6302) -based PROTACs. Incorporates a fluoro leaving group to allow conjugation to amine linker. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
276.22
Formula:
C13H9FN2O4
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
835616-60-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Degradation of the BAF complex factor BRD9 by heterobifunctional ligands.
    Remillard et al.
    Angew.Chem.Int.Ed.Engl., 2017;56:5738

Product Datasheets

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