Potent, reversible inhibitor of fatty acid amide hydrolase (FAAH) (IC50
values are 28 and 100 nM for human and rat FAAH respectively). Noncovalent inhibitor; displays selectivity for FAAH over cannabinoid-related targets (IC50
> 20 μ
M for CB1
and TRPV1). Active in vivo
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH).
Min et al.
Identification of potent, noncovalent fatty acid amide hydrolase (FAAH) inhibitors.
Gustin et al.