TC-I 2014

Catalog # Availability Size / Price Qty
5410/10
5410/50
Cat.No. 5410 - TC-I 2014 | C23H19F6N3O | CAS No. 1221349-53-6
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Description: Potent TRPM8 antagonist

Chemical Name: 3-[7-(Trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-benzimidazol-2-yl]-1-oxa-2-azaspiro[4.5]dec-2-ene

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Biological Activity

Potent TRPM8 antagonist (IC50 values are 0.8, 3.0 and 4.4 nM for canine, human and rat channels respectively). Exhibits antiallodynic properties in pain models in vivo.

Technical Data

Formula:
C23H19F6N3O
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage:
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
CAS No:
1221349-53-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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