Human TRPM8 (Q7Z2W7) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC0188
Product Details
Citations (1)
FAQs
Supplemental Products
Reviews

Human TRPM8 (Q7Z2W7) VersaClone cDNA Summary

TRPM8 functions as a cold receptor in sensory neurons but is also expressed in tissues not exposed to ambient temperatures, as well as in cancer tissues. TRPM8 is expressed in prostate and in most in prostate tumors. TRPM8 is also expressed in non-prostatic primary tumors such as colon, lung, breast and skin tumors. There are two shorter splice variants of TRPM8, termed short TRPM8a and short TRPM8 beta. Both variants are in a closed configuration with the C-terminal tail of the full-length TRPM8 channel, resulting in stabilization of its closed state and thus reducing both its cold sensitivity and activity. The sensation of coolness triggered by eucalyptol or menthol may be explained by the fact that menthol and cool temperatures sensations are detected by this protein.

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

Product Datasheets

Background: TRPM8

Entrez Gene IDs
79054 (Human); 171382 (Mouse); 171384 (Rat)
Alternate Names
CMR1; Long transient receptor potential channel 6; LTRPC6; LTrpC-6; MGC2849; short form of the TRPM8 cationic channel; transient receptor potential cation channel, subfamily M, member 8; Transient receptor potential p8; transient receptor potential subfamily M member 8; TRPM8; TRPP8; trp-p8; TRPP8transient receptor potential cation channel subfamily M member 8

Citation for Human TRPM8 (Q7Z2W7) VersaClone cDNA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Activation of host transient receptor potential (TRP) channels by praziquantel stereoisomers
    Authors: GS Gunaratne, NA Yahya, PI Dosa, JS Marchant
    PLoS Negl Trop Dis, 2018;12(4):e0006420.  2018

FAQs

No product specific FAQs exist for this product, however you may

View all cDNA Clone FAQs

Reviews for Human TRPM8 (Q7Z2W7) VersaClone cDNA

There are currently no reviews for this product. Be the first to review Human TRPM8 (Q7Z2W7) VersaClone cDNA and earn rewards!

Have you used Human TRPM8 (Q7Z2W7) VersaClone cDNA?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review