TCR V delta 2 Antibody (B6) - BSA Free

Novus Biologicals | Catalog # NBP3-11706

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # B6

Format

BSA Free
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Product Specifications

Immunogen

Human recombinant TCR Vdelta2

Specificity

The mouse monoclonal antibody B6 recognizes an extracellular epitope of human TCR V delta 2, which is expressed on the majority of gamma/delta T cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for TCR V delta 2 Antibody (B6) - BSA Free

Flow Cytometry: TCR V delta 2 Antibody (B6) - BSA Free [NBP3-11706]

Flow Cytometry: TCR V delta 2 Antibody (B6) - BSA Free [NBP3-11706]

Flow Cytometry: TCR V delta 2 Antibody (B6) [NBP3-11706] - Separation of human TCR Vdelta2 positive lymphocytes (red-filled) from human TCR Vdelta2 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of peripheral whole blood stained using anti-human TCR Vdelta2 (B6) purified antibody (concentration in sample 0,3 ug/ml, GAM APC).
Flow Cytometry: TCR V delta 2 Antibody (B6) - BSA Free [NBP3-11706]

Flow Cytometry: TCR V delta 2 Antibody (B6) - BSA Free [NBP3-11706]

Flow Cytometry: TCR V delta 2 Antibody (B6) [NBP3-11706] - Surface staining pattern of human peripheral whole blood stained using anti-human TCR Vdelta2 (B6) purified antibody (concentration in sample 0,3 ug/ml, GAM APC).
Flow Cytometry: TCR V delta 2 Antibody (B6) - BSA Free [NBP3-11706]

Flow Cytometry: TCR V delta 2 Antibody (B6) - BSA Free [NBP3-11706]

Flow Cytometry: TCR V delta 2 Antibody (B6) [NBP3-11706] - Multicolor surface staining pattern of human lymphocytes using anti-human TCR Vdelta2 (B6) purified antibody (concentration in sample 0,3 ug/ml, GAM APC) and anti-human CD3 (UCHT1) PE antibody (4 ul reagent / 100 ul of peripheral whole blood).

Applications for TCR V delta 2 Antibody (B6) - BSA Free

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

Phosphate buffered saline (PBS), pH 7.4

Format

BSA Free

Preservative

15mM Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: TCR V delta 2

TCR V delta 2 is a variant of TCR delta chain, that is present on a major subset of human gamma/delta T cells. TCR Vgamma9/Vdelta2 (or Vgamma2/Vdelta2) T cells are able to recognize and kill various tumor cells, as this receptor heterodimer binds to certain phosphoantigens, expressed by tumors. They can recognize these antigens in an MHC-unrestricted manner. Similarly to NK cells, Vdelta2 T cells express MHC I receptors and killer Ig-like receptors, that are involved in tumor recognition and cytolysis. The potently cytotoxic subset of them is identified by cell surface expression of polysialyated CD56.

Alternate Names

hDV102S1

Gene Symbol

TRDV2

Additional TCR V delta 2 Products

Product Documents for TCR V delta 2 Antibody (B6) - BSA Free

Certificate of Analysis

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Product Specific Notices for TCR V delta 2 Antibody (B6) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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