TCS ERK 11e
Chemical Name: 4-[2-[(2-Chloro-4-fluorophenyl)amino]-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide
Biological ActivityPotent and selective extracellular signal-related kinase 2 (ERK2) inhibitor (K i values are <2, 395, 540 and 852 nM for ERK2, GSK-3, Aurora Kinase A and Cdk2 respectively). Potently blocks proliferation of HT29 cells (IC 50 = 48 nM). Orally bioavailable.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-related kinase (ERK) using conformational control.
Aronov et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for TCS ERK 11e
There are currently no reviews for this product. Be the first to review TCS ERK 11e and earn rewards!
Have you used TCS ERK 11e?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image