TCS OX2 29

Catalog # Availability Size / Price Qty
3371/10
3371/50
OX2 Receptor Antagonists Small Molecule
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Description: Potent and selective OX2 antagonist

Chemical Name: (2S)-1-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3,3-dimethyl-2-[(4-pyridinylmethyl)amino]-1-butanone hydrochloride

Purity: ≥98%

Product Details
Citations (8)
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Biological Activity

Potent and selective OX2 receptor antagonist (IC50 = 40 nM). Displays >250-fold selectivity for OX2 over OX1 and a range of receptors, ion channels and transporters. Inhibits orexin A induced IP3 accumulation and ERK1/2 phosphorylation in CHO cells transfected with the OX2 receptor.

Technical Data

M.Wt:
433.97
Formula:
C23H31N3O3.HCl
Solubility:
Soluble to 100 mM in water and to 25 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at +4°C
CAS No:
1610882-30-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for TCS OX2 29

The citations listed below are publications that use Tocris products. Selected citations for TCS OX2 29 include:

8 Citations: Showing 1 - 8

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